Causes of Fibromyalgia (Contd.)
Fibromyalgia and Neurochemicals
Fibromyalgia may be related to pain neurochemicals. Researchers have found elevated levels of spinal fluid substance P, a kind of pain amplifier; lower-than-normal levels of serum serotonin, and low production of cortisol (a hormone that helps our bodies respond to stress).
Fibromyalgia and Impaired Energy Production
Researchers have noticed changes in energy metabolism in red blood cells and muscle cells associated with fibromyalgia. Some suggest that damage to the cells' energy production in the mitochondria (the energy production center of the cells), as a result of an excess of free radicals, may be the primary cause of fibromyalgia.
Fibromyalgia and Impaired Circulation to the Muscle Cells
Reduced circulation to muscle cells is also suggested as contributing to fibromyalgia. The metabolic shutdown in the muscle cells might possibly be due to the accumulation of phosphate and uric acid. Aluminum toxicity is also suggested as playing a role in the genesis of fibromyalgia. Food toxicity may also be a contributing factor.
There is increasing evidence that people with fibromyalgia have unfit or poorly developed muscles. It is not yet known whether unfit muscles are the cause or the result of fibromyalgia. Nonetheless, this fact is very important; it suggests that people who are able to engage in a regular exercise program will see major improvement in their symptoms.
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