If your sores are caused by a vitamin or mineral deficiency, supplements of vitamins C and B complex, as well as folic acid, iron, and zinc, may help.
Several studies have found a high incidence of iron and B vitamin deficiency among people with recurrent mouth ulcers. Supplementing with B vitamins-300 mg vitamin B1, 20 mg vitamin B2, and 150 mg vitamin B6-has been reported to provide some people with relief. Thiamine (B1) deficiency, specifically, has been linked to an increased risk.
Some people with recurrent mouth ulcers have been reported to respond to lactobacillus acidophilus. Chewing four lactobacillus tablets three times per day may reduce soreness in some people with recurrent mouth ulcers.
Take 1,000 milligrams of the amino acid lysine at each meal during an outbreak and then 500 milligrams at each meal for a week afterward.
Rub the liquid from a vitamin E capsule directly on the sore. Apply it three times a day during an outbreak until the sore heals.
Take 4,000 - 5,000 milligrams of vitamin C daily during outbreaks of canker sores and at least 500 milligrams daily as a way of preventing them.
Zinc lozenges help resolve canker sores by supporting the immune system.
Calcium supplements help counteract the overacidity.
Suggested Daily Dosages:
Vitamin B complex
Extra vitamin B3 (niacin)
Pantothenic acid (vitamin B5)
Vitamin C with bioflavonoids
Aqueous colloidal silver
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